T8 Killer Lymphocyte Perfusion Culture

References :

4-1BB Is Superior to CD28 Costimulation for Generating CD8+ Cytotoxic Lymphocytes for Adoptive Immunotherapy

Rapid production of clinical grade T lymphocytes in a wave bioreactor

Preferential T cell expansion by artificial antigen presenting cells expressing 4-1BBL alone or in combination with CD80 or CD86

In vitro development of B lymphocytes from long term cutured precursor cells

Substantial Differences in Specificity of HIV-specific Cytotoxic T Cells in Acute and Chronic HIV Infection

Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones

Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells

Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs

Long-term in vivo provision of antigen-specific T cell immunity by programming hematopoietic stem cells

Cytotoxic T Lymphocyte Therapy for Epstein-Barr Virus+ Hodgkin’s Disease

Treatment of nasopharyngeal carcinoma with Epstein-Barr virus–specific T lymphocytes

Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals.

In vivo migration and function of transferred HIV-1-specific cytotoxic T cells